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9\u670823\u53f7\uff0c\u5357\u4eac\u7684\u98ce\u88f9\u7740\u6ee1\u8857\u7684\u6842\u82b1\u9999\u5f80\u751f\u79d1\u9662\u8d70\u5eca\u94bb\u7684\u65f6\u5019\uff0c\u6211\u6b63\u8e72\u5728\u5899\u6839\u6252\u534a\u76d2\u51c9\u900f\u7684\u9ec4\u7116\u9e21\u7c73\u996d\u3002\u5bf9\u9762\u7684\u5e08\u59b9\u521a\u6362\u5b8c\u5b9e\u9a8c\u670d\uff0c\u6458\u4e86\u4e73\u80f6\u624b\u5957\u5c31\u5f80\u6211\u65c1\u8fb9\u4e00\u5750\uff0c\u8bf4\u6628\u5929\u63a5\u4e86\u4e2a\u79d1\u666e\u91c7\u8bbf\uff0c\u88ab\u8bb0\u8005\u8ffd\u7740\u95ee\u4e86\u4e09\u4e2a\u5c0f\u65f6”\u73b0\u5728\u7684\u57fa\u56e0\u7f16\u8f91\u662f\u4e0d\u662f\u80fd\u968f\u4fbf\u6539\u5c0f\u5b69\u7684\u957f\u76f8\u548c\u667a\u5546”\uff0c\u7ed9\u5979\u95ee\u5f97\u8fde\u665a\u996d\u90fd\u6ca1\u80c3\u53e3\u5403\u3002<\/p>\n

\u522b\u628a\u5b83\u5f53”\u751f\u7269\u7248PS”\uff0c\u5dee\u8fdc\u4e86<\/h2>\n

\u597d\u591a\u4eba\u5bf9\u57fa\u56e0\u7f16\u8f91\u7684\u60f3\u8c61\uff0c\u771f\u7684\u8ddf\u65e9\u5e74\u628aPS\u5f53”\u6362\u8138\u795e\u5668”\u7684\u8ba4\u77e5\u5dee\u4e0d\u591a\u2014\u2014\u54ea\u91cc\u4e0d\u6ee1\u610f\u70b9\u54ea\u91cc\uff0c\u628a\u584c\u9f3b\u6881\u62c9\u9ad8\uff0c\u628a\u667a\u5546\u6761\u62c9\u6ee1\uff0c\u8fde\u8870\u8001\u90fd\u80fd\u4e00\u952e\u4fee\u6389\u3002<\/p>\n

\u4f46\u771f\u8e72\u5728\u5b9e\u9a8c\u5ba4\u770b\u4e86\u4e09\u6b21\u5b8c\u6574\u7684CRISPR\u64cd\u4f5c\u6d41\u7a0b\u4e4b\u540e\uff0c\u6211\u53ea\u80fd\u8bf4\uff0c\u8fd9\u4e2a\u8bef\u4f1a\u5927\u5230\u79bb\u8c31\u3002\u5b83\u7684\u5de5\u4f5c\u903b\u8f91\u6839\u672c\u4e0d\u662f”\u65e0\u4e2d\u751f\u6709\u9020\u4e2a\u65b0\u57fa\u56e0”\uff0c\u800c\u662f\u627e\u5230\u57fa\u56e0\u7ec4\u4e0a\u67d0\u6bb5\u51fa\u95ee\u9898\u7684\u5e8f\u5217\uff0c\u5494\u5693\u526a\u6389\uff0c\u518d\u8865\u4e0a\u6b63\u786e\u7684\u7247\u6bb5<\/strong>\u3002\u8bf4\u767d\u4e86\u5c31\u662f\u4e2a\u5e26\u5bfc\u822a\u7684\u5c0f\u526a\u5200\uff0c\u8ddf\u4f60\u5728Word\u91cc\u627e\u9519\u522b\u5b57\u6539\u4e2a\u9519\u5b57\u7684\u903b\u8f91\u6ca1\u5dee\u3002<\/p>\n\n\n

\"CRISPR\u57fa\u56e0\u7f16\u8f91\u9776\u5411\u8bc6\u522b\u5e76\u5207\u5272\u7279\u5b9aDNA\u5e8f\u5217\u7684\u539f\u7406\u793a\u610f\u56fe\"
CRISPR\u57fa\u56e0\u7f16\u8f91\u9776\u5411\u8bc6\u522b\u5e76\u5207\u5272\u7279\u5b9aDNA\u5e8f\u5217\u7684\u539f\u7406\u793a\u610f\u56fe<\/figcaption><\/figure>\n\n

\u771f\u6ca1\u90a3\u4e48\u795e\u3002<\/p>\n

\u4e3e\u4e2a\u6700\u5e38\u89c1\u7684\u4f8b\u5b50\uff0c\u9570\u5200\u578b\u8d2b\u8840\u7684\u75c5\u6839\uff0c\u5c31\u662f\u8d1f\u8d23\u5408\u6210\u8840\u7ea2\u86cb\u767d\u7684\u90a3\u6bb5\u57fa\u56e0\u9519\u4e86\u4e00\u4e2a\u78b1\u57fa\u2014\u2014\u5c31\u50cf\u4f60\u6253\u957f\u6587\u7684\u65f6\u5019\u628a”\u7684”\u6253\u6210\u4e86”\u5730”\uff0c\u6574\u53e5\u8bdd\u7684\u610f\u601d\u76f4\u63a5\u6b6a\u4e86\u3002\u57fa\u56e0\u7f16\u8f91\u8981\u505a\u7684\uff0c\u5c31\u662f\u7cbe\u51c6\u627e\u5230\u90a3\u4e2a\u9519\u5b57\uff0c\u628a\u5b83\u6539\u56de\u6b63\u786e\u7684\u7248\u672c\u3002<\/p>\n

\u8981\u662f\u60f3\u9760\u5b83\u65e0\u4e2d\u751f\u6709\uff0c\u7ed9\u4eba\u52a0\u4e2a\u591c\u89c6\u7684\u57fa\u56e0\uff0c\u52a0\u4e2a\u80fd\u98de\u7684\u57fa\u56e0\uff0c\u90a3\u57fa\u672c\u7b49\u4e8e\u62ff\u8fd9\u628a\u5c0f\u526a\u5200\u53bb\u62c6\u6574\u680b\u697c\u3002\u4eba\u7684\u57fa\u56e0\u7ec4\u670930\u4ebf\u4e2a\u78b1\u57fa\u5bf9\uff0c\u5bfc\u822a\u7a0d\u5fae\u504f\u4e00\u70b9\uff0c\u526a\u5230\u522b\u7684\u5730\u65b9\u53bb\uff0c\u5c31\u662f\u5929\u5927\u7684\u9ebb\u70e6\u3002\u6211\u7b2c\u4e00\u6b21\u5728\u663e\u5fae\u955c\u4e0b\u770b\u5230\u88ab\u526a\u9519\u4f4d\u7f6e\u7684\u7ec6\u80de\u65f6\uff0c\u9e21\u76ae\u7599\u7629\u90fd\u8d77\u6765\u4e86\u3002<\/p>\n

\u592a\u8106\u4e86\u3002<\/p>\n

2019\u5e74\u5c31\u6709\u7814\u7a76\u56e2\u961f\u516c\u5f00\u8fc7\u5b9e\u9a8c\u7ed3\u679c\uff0c\u90e8\u5206CRISPR\u64cd\u4f5c\u4f1a\u89e6\u53d1\u7ec6\u80de\u81ea\u8eab\u7684DNA\u635f\u4f24\u5e94\u7b54\uff0c\u4e00\u4e0d\u5c0f\u5fc3\u5c31\u4f1a\u78b0\u574f\u7ec6\u80de\u91cc\u7684\u6291\u764c\u57fa\u56e0\u5f00\u5173\uff0c\u672c\u6765\u597d\u597d\u7684\u6b63\u5e38\u7ec6\u80de\uff0c\u76f4\u63a5\u5c31\u5f80\u764c\u53d8\u7684\u65b9\u5411\u8dd1\u3002\u4f60\u4ee5\u4e3a\u662f\u5728\u505a\u7f8e\u5bb9\uff0c\u641e\u4e0d\u597d\u662f\u5728\u7ed9\u764c\u7ec6\u80de\u5f00\u95e8\u3002<\/p>\n\n\n

\"CRISPR\u7f16\u8f91\u8fc7\u7a0b\u4e2d\u8131\u9776\u5bfc\u81f4DNA\u7247\u6bb5\u9519\u8bef\u62fc\u63a5\u7684\u663e\u5fae\u6210\u50cf\u56fe\"
CRISPR\u7f16\u8f91\u8fc7\u7a0b\u4e2d\u8131\u9776\u5bfc\u81f4DNA\u7247\u6bb5\u9519\u8bef\u62fc\u63a5\u7684\u663e\u5fae\u6210\u50cf\u56fe<\/figcaption><\/figure>\n\n

\u8bf4\u771f\u7684\uff0c\u6211\u7279\u522b\u7406\u89e3\u5927\u5bb6\u5bf9\u8fd9\u79cd\u6280\u672f\u7684\u597d\u5947\uff0c\u4f46\u771f\u522b\u628a\u5b83\u60f3\u6210\u65e0\u6240\u4e0d\u80fd\u7684\u9b54\u6cd5\u3002\u5c31\u50cf\u4f60\u62ff\u83dc\u5200\u5207\u83dc\u5f88\u987a\u624b\uff0c\u603b\u4e0d\u80fd\u89c9\u5f97\u62ff\u5b83\u5c31\u80fd\u628a\u623f\u5b50\u62c6\u4e86\u5427\uff1f<\/p>\n

\u90a3\u4e9b\u5439\u5f97\u5929\u82b1\u4e71\u5760\u7684\u5546\u4e1a\u9879\u76ee\uff0c\u57fa\u672c\u90fd\u662f\u5728\u5272\u97ed\u83dc<\/h2>\n

\u4e0a\u4e2a\u6708\u6709\u4e2a\u8bfb\u8005\u7ed9\u6211\u53d1\u79c1\u4fe1\uff0c\u8bf4\u4ed6\u88ab\u670b\u53cb\u62c9\u53bb\u542c\u4e86\u4e2a”\u524d\u6cbf\u751f\u7269\u79d1\u6280”\u7684\u63a8\u4ecb\u4f1a\uff0c\u53f0\u4e0a\u7684\u4eba\u62ff\u7740\u4e2aPPT\uff0c\u8bf4\u53ea\u8981\u82b1198\u4e07\uff0c\u5c31\u80fd\u901a\u8fc7\u57fa\u56e0\u7f16\u8f91\u628a\u4ed6\u7684\u9057\u4f20\u6027\u9ad8\u8840\u538b\u7ed9\u6cbb\u597d\uff0c\u8fd8\u80fd\u987a\u4fbf\u4f18\u5316\u4ed6\u513f\u5b50\u7684\u57fa\u56e0\uff0c\u8ba9\u4ee5\u540e\u8003\u6e05\u534e\u7a33\u4e0a\u3002\u6211\u5f53\u65f6\u76ef\u7740\u90a3\u4e2a\u6d88\u606f\u770b\u4e86\u534a\u5206\u949f\uff0c\u53ea\u56de\u4e86\u4e00\u53e5\uff1a\u4f60\u73b0\u5728\u8dd1\u8fd8\u6765\u5f97\u53ca\u3002<\/p>\n

\u8bf4\u5b9e\u8bdd\uff0c\u6211\u8ddf\u4f60\u638f\u5fc3\u7a9d\u5b50\u8bb2\uff0c\u73b0\u5728\u6240\u6709\u62ff\u4eba\u505a\u6d3b\u4f53\u57fa\u56e0\u7f16\u8f91\u6cbb\u7597\u975e\u81f4\u547d\u75be\u75c5\u7684\uff0c\u5168\u662f\u9a97\u94b1\u7684\u3002<\/p>\n

\u771f\u4e0d\u662f\u6211\u5634\u786c\u3002\u73b0\u5728\u5168\u7403\u8303\u56f4\u5185\uff0c\u5df2\u7ecf\u83b7\u6279\u4e0a\u5e02\u7684\u57fa\u56e0\u7f16\u8f91\u6cbb\u7597\u4ea7\u54c1\uff0c\u603b\u5171\u5c31\u4e24\u4e2a\uff0c\u90fd\u662f\u9488\u5bf9\u03b2\u5730\u4e2d\u6d77\u8d2b\u8840\u548c\u9570\u5200\u578b\u8d2b\u8840\u7684\u91cd\u75c7\u60a3\u8005\u3002\u6574\u4e2a\u6cbb\u7597\u6d41\u7a0b\u662f\u5565\u6837\u7684\uff1f\u8981\u5148\u628a\u60a3\u8005\u7684\u9020\u8840\u5e72\u7ec6\u80de\u4ece\u9aa8\u9ad3\u91cc\u62bd\u51fa\u6765\uff0c\u5728\u4e25\u683c\u7684\u5b9e\u9a8c\u5ba4\u73af\u5883\u91cc\u628a\u574f\u7684\u57fa\u56e0\u6539\u5bf9\uff0c\u518d\u628a\u60a3\u8005\u81ea\u5df1\u7684\u9aa8\u9ad3\u6e05\u5e72\u51c0\uff0c\u628a\u6539\u597d\u7684\u7ec6\u80de\u8f93\u56de\u53bb\u3002\u6574\u4e2a\u8fc7\u7a0b\u8981\u5728\u65e0\u83cc\u8231\u91cc\u5f85\u4e00\u4e2a\u591a\u6708\uff0c\u6cbb\u7597\u8d39\u6298\u4eba\u6c11\u5e01\u5dee\u4e0d\u591a1500\u4e07\u3002\u8fd9\u4e0d\u662f\u7ed9\u666e\u901a\u4eba\u51c6\u5907\u7684\u6d88\u8d39\u9879\u76ee\uff0c\u662f\u7ed9\u8d70\u6295\u65e0\u8def\u7684\u91cd\u75c7\u60a3\u8005\u7559\u7684\u6700\u540e\u4e00\u6761\u8def\u3002<\/p>\n

\u5f53\u5e74\u90a3\u4e2a\u6539\u4e86CCR5\u57fa\u56e0\u7684\u4e24\u4e2a\u5c0f\u5b69\u7684\u4e8b\uff0c\u73b0\u5728\u60f3\u8d77\u6765\u90fd\u8ba9\u4eba\u89c9\u5f97\u5835\u5f97\u614c\u3002\u90a3\u6b21\u64cd\u4f5c\u6839\u672c\u5c31\u4e0d\u662f\u4ec0\u4e48\u6280\u672f\u7a81\u7834\uff0c\u662f\u62ff\u4e24\u4e2a\u8fd8\u6ca1\u51fa\u751f\u7684\u5b69\u5b50\u7684\u4eba\u751f\uff0c\u6362\u4e86\u4e00\u4e2a\u60f3\u5f53”\u4e16\u754c\u7b2c\u4e00”\u7684\u865a\u540d\u3002\u66f4\u53ef\u7b11\u7684\u662f\uff0c\u597d\u591a\u4eba\u770b\u5b8c\u90a3\u4e2a\u65b0\u95fb\uff0c\u53cd\u800c\u89c9\u5f97\u57fa\u56e0\u7f16\u8f91\u5df2\u7ecf\u5389\u5bb3\u5230\u80fd\u968f\u4fbf\u6539\u4eba\u4e86\uff0c\u8f6c\u5934\u5c31\u7ed9\u9a97\u5b50\u9001\u94b1\u3002<\/p>\n

\u633a\u8352\u8bde\u7684\u3002<\/p>\n

\u597d\u591a\u4eba\u6015\u7684”\u5b9a\u5236\u5a74\u513f”\uff0c\u5176\u5b9e\u5c31\u73b0\u5728\u7684\u6280\u672f\u6c34\u5e73\uff0c\u8fde\u5165\u95e8\u7684\u8fb9\u90fd\u6478\u4e0d\u5230\u3002\u4f60\u60f3\u554a\uff0c\u667a\u5546\u3001\u957f\u76f8\u8fd9\u4e9b\u6027\u72b6\uff0c\u6839\u672c\u4e0d\u662f\u5355\u4e2a\u57fa\u56e0\u80fd\u63a7\u5236\u7684\uff0c\u662f\u51e0\u767e\u4e0a\u5343\u4e2a\u57fa\u56e0\u4e92\u76f8\u4f5c\u7528\uff0c\u518d\u53e0\u52a0\u4e0a\u5341\u51e0\u5e74\u7684\u5bb6\u5ead\u73af\u5883\u3001\u6559\u80b2\u7ecf\u5386\u5806\u51fa\u6765\u7684\u7ed3\u679c\u3002\u4f60\u786c\u8981\u9760\u7f16\u8f91\u57fa\u56e0\u6539\u8fd9\u4e9b\uff0c\u6307\u4e0d\u5b9a\u6539\u5b8c\u4e4b\u540e\uff0c\u5c0f\u5b69\u7684\u514d\u75ab\u7cfb\u7edf\u76f4\u63a5\u51fa\u5927\u95ee\u9898\u3002<\/p>\n

\u771f\u6b63\u7684\u4ef7\u503c\uff0c\u4ece\u6765\u90fd\u4e0d\u5728”\u9020\u8d85\u4eba”\u7684\u5e7b\u60f3\u91cc<\/h2>\n

\u6211\u8fd9\u51e0\u5e74\u8dd1\u5b9e\u9a8c\u5ba4\uff0c\u89c1\u8fc7\u7684\u505a\u57fa\u56e0\u7f16\u8f91\u7684\u8001\u5e08\uff0c\u6ca1\u51e0\u4e2a\u5728\u804a\u4ec0\u4e48”\u4eba\u7c7b\u8fdb\u5316””\u5b9a\u5236\u5a74\u513f”\u7684\u3002\u5927\u5bb6\u804a\u7684\u90fd\u662f\u5565\uff1f\u600e\u4e48\u628a\u8131\u9776\u7684\u6982\u7387\u518d\u538b\u4e00\u538b\uff0c\u600e\u4e48\u628a\u73b0\u5728\u4e0a\u767e\u4e07\u7684\u6cbb\u7597\u6210\u672c\u780d\u5230\u51e0\u4e07\u5757\uff0c\u600e\u4e48\u628a\u519c\u4e1a\u4e0a\u7684\u5e94\u7528\u518d\u5f80\u524d\u63a8\u4e00\u6b65\u3002<\/p>\n\n\n

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